"Functional Amyloid"

“Functional amyloid” is a term I first heard about 3 years ago at the XII Amyloidosis Symposium in Rome. There was an oral presentation about the organization of peptide hormones in the secretory granules of the pituitary. Prior to that, I , like most …

New Amyloid Fibril Nomenclature Recommendations Published

In May of 2012, at the XIIIth International Symposium on Amyloidosis in Groningen (Netherlands), the Nomenclature Committee of the International Society of Amyloidosis updated amyloid fibril nomenclature guidelines, and expanded the list of recognized amyloid fibril subtypes. The latter is shown here in 3 tables from the article

From Sipe J.D., et al. Amyloid, 2012; 19(4): 167–170
From Sipe J.D., et al. Amyloid, 2012; 19(4): 167–170
From Sipe J.D., et al. Amyloid, 2012; 19(4): 167–170

 I wanted to post the Amyloid Fibril Protein Nomenclature List because it serves as a reference for readers, and also provides context for the broad range of medical topics which will be discussed over time in this blog. Keep this post handy!

Suffering from TE

I am suffering from progressive intermittent Theralite Envy (TE), a recently-recognized condition amongst American clinicians who treat a lot of myeloma patients but do not have ready access to the Gambro HCO 1100 dialyzer filter.  The cause of TE…

9 years and counting….

The last U.S.-led randomized study comparing different treatments for newly-diagnosed AL amyloidosis was published in 2004. The one before that was published in 1999. Two randomized studies, 14 years. To put this in some perspective, despite the fact t…