I was at the Hospital on Liverpool on Friday where I got the results of my latest paraprotein levels. Guess what! They have gone up again. They were 13 now they are 23. They will probably continue to rise.
There are a couple of things that we are going to do, we being the doctors and me. The first is to increase the steroids that I am on with the Lenalidomide, I’m not back on the three day pulse of 40mg, which is 20 tablets for three days at a time. They are hoping that this will stabilise the paraprotein as the combination of steroids and Lenalidomide is the way that they manage it’s effectiveness. I’m already on the full strength of Lenalidomide, so they have changed the Dexamethasone to see if that works.
The other things that we are going to do is a mini transplant or Donor Lymphocyte Infusion (DLI). A DLI involves extracting the white cells from my Donor (My brother Nigel in my case) and infusing them into me. Nigel will have to go on the same machine he did last time that extracted his bone marrow, but he wont need to have the injection he had last time as it will just be extracting the white cells.
Once the cell have been extracted they are infused into me, the same way as